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Epidemiology

Members

Rigmor Jensen, Sait Ashina, Asif Munir Shah.

Background
Epidemiology is the study of the distribution and determinants of health-related states or events in specified populations. The Glostrup County population study from 1989 was the first prevalence study of specific headache entities in a representative general population, based on a structured interview and examination by a physician. This study demonstrated the huge impact headache has on individuals and society.

A follow-up study showed an increase in frequency and health care utilisation and thereby indicated a higher impact of headache over a 12-year period. Risk factors for migraine were young age, female gender, familial disposition, no vocational education, high work load and frequent tensiontype headache. For tension-type headache risk factors were young age, female gender, poor self-rated health, inability to relax after work, and sleeping fewer hours per night. In general migraine and tension-type headache had a favourable prognosis with increasing age and only a minority of subjects had increased headache frequency. Prognostic factors were identified.


Current projects
Supplementary data analysis of the large follow-up study is ongoing with specific focus on chronification, clinical headache characteristics and socioeconomic impact. A large clinical study of patients treated at the Danish Headache Center has already been conducted with main focus on medication overuse headache.

It has been demonstrated that detoxification have a very positive outcome, especially in migraineurs and that these patients becomes reactive to migraine prophylactics again. Several new projects focusing on specific treatment results and neurobiological mechanisms underlying medication overuse headache are ongoing. Data from the epidemiological studies are related to newer population studies and predictors for chronification are searched.

 




Redaktør
Ditte Sjølund
Email RVYcioap@3pm.regionh.dk